Ibrunat 140 mg Capsules

Ibrunat 140 mg Capsules contain the active ingredient Ibrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor. Ibrutinib works by blocking BTK, a protein essential for the growth and survival of certain cancer cells, thereby inhibiting their proliferation and inducing apoptosis.

Indications:

Ibrunat 140 mg Capsules are indicated for the treatment of specific blood cancers, including:

• Chronic Lymphocytic Leukemia (CLL)
• Mantle Cell Lymphoma (MCL)
• Waldenström’s Macroglobulinemia (WM)

Dosage and Administration:

The dosage of Ibrunat 140 mg Capsules varies based on the specific condition and patient response. It’s crucial to follow the prescribing physician’s instructions regarding dosage and duration. Typically, the capsules are taken orally with water, with or without food, at a consistent time each day.

Possible Side Effects:

Common side effects may include:

• Diarrhea
• Fatigue
• Muscle pain
• Nausea

Patients should promptly report any severe or persistent side effects to their healthcare provider.

Precautions:

• Alcohol: Consult your doctor regarding the consumption of alcohol while on this medication.
• Pregnancy: Not recommended during pregnancy due to potential risks to the developing baby.
• Breastfeeding: Use with caution; breastfeeding should be discontinued during treatment and until the drug is eliminated from the mother’s body.
• Driving: May cause side effects that could affect your ability to drive; exercise caution.
• Kidney and Liver: Use with caution in patients with kidney or liver disease; dose adjustments may be necessary.

Drug Interactions:

Ibrunat may interact with various medications, including:

• Antifungal agents (e.g., ketoconazole, voriconazole)
• Antibiotics (e.g., clarithromycin)
• Antidepressants (e.g., nefazodone, fluvoxamine)
• Antiepileptic drugs (e.g., phenytoin)
• Herbal supplements containing St. John’s Wort

Patients should inform their healthcare provider about all medications and supplements they are taking to avoid potential interactions.

Storage:

Store Ibrunat 140 mg Capsules in a cool, dry place away from direct sunlight. Keep out of reach of children and pets.

Packaging and Manufacturer:

• Brand Name: Ibrunat
• Generic Name: Ibrutinib (140 mg)
• Manufacturer: Natco Pharma Ltd
• Packaging: 30 capsules per bottle

Note: Prices are subject to change and may vary between pharmacies. Consult your healthcare provider before starting any new medication to ensure it’s appropriate for your condition.